[5] Harlequins 26-24 London Irish [12] 2022-10-29 14:00
Stadium: London Round: 8
Referee: Craig Maxwell-Keys
Head to Head
| Premiership Rugby Cup | 2022/09/21 18:45 | Harlequins v London Irish | L | 26-30 |
| Premiership Rugby | 2022/04/03 14:00 | London Irish v Harlequins | W | 14-41 |
| Premiership Rugby Cup | 2022/03/18 19:45 | London Irish v Harlequins | L | 34-19 |
| Premiership Rugby | 2021/11/27 15:00 | Harlequins v London Irish | L | 19-22 |
| Premiership Rugby | 2021/04/24 11:30 | London Irish v Harlequins | W | 21-25 |
| Premiership Rugby | 2021/01/10 15:00 | Harlequins v London Irish | D | 27-27 |
| Premiership Rugby | 2020/09/09 18:45 | London Irish v Harlequins | W | 15-38 |
| Premiership Rugby | 2020/02/15 15:00 | Harlequins v London Irish | L | 15-29 |
| Premiership Rugby Cup | 2019/09/28 14:00 | London Irish v Harlequins | W | 18-21 |
| Premiership Rugby | 2018/04/07 14:00 | Harlequins v London Irish | L | 5-35 |
| Premiership Rugby | 2017/09/02 15:45 | London Irish v Harlequins | L | 39-29 |
| Premiership Rugby | 2016/05/01 14:00 | London Irish v Harlequins | W | 25-32 |
| European Rugby Challenge Cup | 2016/04/09 19:05 | Harlequins v London Irish | W | 38-30 |
| Premiership Rugby | 2015/12/05 15:00 | Harlequins v London Irish | W | 38-7 |
| Premiership Rugby | 2015/03/07 15:00 | Harlequins v London Irish | W | 26-20 |
| Premiership Rugby | 2014/09/06 15:30 | London Irish v Harlequins | W | 15-20 |
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