[5] Exeter Chiefs 21-33 London Irish [10] 2021-10-23 14:00
Stadium: Sandy Park Round: 6
Referee: Hamish Smales
Head to Head
| Premiership Rugby | 2021/05/18 18:45 | London Irish v Exeter Chiefs | W | 12-31 |
| Premiership Rugby | 2021/02/13 16:15 | Exeter Chiefs v London Irish | W | 26-3 |
| Premiership Rugby | 2020/09/30 16:30 | Exeter Chiefs v London Irish | L | 19-22 |
| Premiership Rugby | 2020/01/05 14:30 | London Irish v Exeter Chiefs | W | 28-45 |
| Premiership Rugby | 2018/04/15 14:00 | London Irish v Exeter Chiefs | W | 5-45 |
| Premiership Rugby | 2017/09/09 14:00 | Exeter Chiefs v London Irish | W | 37-7 |
| Premiership Rugby | 2016/02/21 15:00 | London Irish v Exeter Chiefs | W | 15-22 |
| Premiership Rugby | 2015/10/24 17:00 | Exeter Chiefs v London Irish | W | 38-11 |
| Premiership Rugby | 2015/01/11 15:00 | London Irish v Exeter Chiefs | L | 28-26 |
| Premiership Rugby | 2014/10/11 14:00 | Exeter Chiefs v London Irish | W | 44-24 |
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