Stadium: JPS Field at Malone Stadium Round: 1
Home Manager: Terry Bowden Away Manager: Deion Sanders
| NCAAF | 2021/09/11 23:00 | Jackson State v Tennessee State | W | 38-16 |
| NCAAF | 2021/09/05 19:00 | Jackson State v Florida A&M | W | 7-6 |
| NCAAF | 2021/04/10 19:00 | Alabama v Jackson State | L | 52-43 |
| NCAAF | 2021/04/03 21:00 | Southern v Jackson State | L | 34-14 |
| NCAAF | 2021/03/20 20:00 | Jackson State v Alabama State | L | 28-35 |
| NCAAF | 2021/03/14 19:00 | Mississippi Valley State v Jackson State | W | 7-43 |
| NCAAF | 2021/03/06 18:00 | Jackson State v Grambling State | W | 33-28 |
| NCAAF | 2021/02/21 19:00 | Jackson State v Edward Waters Tigers | W | 53-0 |
| NCAAF | 2021/09/04 16:00 | UL Monroe v Kentucky | L | 10-45 |
| NCAAF | 2020/12/05 20:00 | UL Monroe v Arkansas State | L | 15-48 |
| NCAAF | 2020/11/28 20:00 | Lafayette v UL Monroe | L | 70-20 |
| NCAAF | 2020/11/07 17:00 | UL Monroe v Georgia State | L | 34-52 |
| NCAAF | 2020/10/31 20:00 | Appalachian St v UL Monroe | L | 31-13 |
| NCAAF | 2020/10/24 23:00 | UL Monroe v South Alabama | L | 14-38 |
| NCAAF | 2020/10/10 16:00 | UL Monroe v Libertay | L | 7-40 |
| NCAAF | 2020/10/03 23:00 | Georgia Southern v UL Monroe | L | 35-30 |