Stadium: Strawberry Stadium Round: 1
Home Manager: Frank Scelfo Away Manager: Tim Rebowe
| NCAAF | 2022/11/18 00:00 | SE Louisiana v Nicholls State | L | 40-17 |
| NCAAF | 2021/11/19 00:00 | Nicholls State v SE Louisiana | W | 45-42 |
| NCAAF | 2021/10/09 17:00 | SE Louisiana v Nicholls State | L | 58-48 |
| NCAAF | 2021/04/10 20:00 | SE Louisiana v Nicholls State | L | 52-45 |
| NCAAF | 2019/11/22 00:00 | Nicholls State v SE Louisiana | W | 28-27 |
| NCAAF FCS | 2018/11/16 00:00 | SE Louisiana v Nicholls State | W | 0-44 |
| NCAAF | 2017/11/17 00:00 | SE Louisiana v Nicholls State | L | 21-17 |